21st May 2014 BSBMT Scientific Day & Open Meeting

Presentations now available with permissions. More to follow..

Session 1: Transplant for Acute Lymphoblastic Leukaemia

The role of transplant for Ph+ve ALL in the era of TKI’sDr Dell Fielding, Royal Free Hospital

– The significance of MRD pre/post-transplant in ALL – a paediatric perspective – Dr Adriana Balduzzi, San Gerardo Hospital, Italy

– Antibody based therapy for ALL – Dr Johannes Dull, University of Wurzburg, Germany

– CD19CAR T-cell therapy for ALL – Professor Stephan Grupp, Children’s Hospital of Philadelphia, USA

Session 2: BSBMT Open Meeting

President’s Report – Prof Gordon Cook
CTC Report – Prof Gordon Cook on behalf of Dr Bronwen Shaw
Treasurer’s Report – Dr Fiona Dignan
Data Registry Report – Mrs Keiren Kirkland

Session 3:The John Goldman Abstract Prize

Cytomegalovirus promotes expansion of pre-exisitng T cell immunity following allogeneic transplantation significantly modulating chimerism statusDr Rob Seller, University College London

– Immunotherapy with CD19CAR EBV CTLs after stem cell transplant in children with high-risk ALL: initial results of the CD19TPALL Study – Dr Juliana Silva, GOSH

– Phenotypic and functional charterisation of alloantigen-specif regulatory T cells expanded after in vitro anergisation with co-stimulatory molecule blockade – Dr Eleni Kotsiou, Barts Cancer Institute

– Silencing the glucocorticoid receptor gene in virus-specific T cells – Dr Laurie Menger, UCL Cancer Institute

– A systems immunology approach to graft-versus-host disease – Dr Pedro Santos-Sousa, University College London Abstract Prize Winner!

– Development of anti-human c-Kit antibodies as conditioning agents for stem cell transplant – Dr Jenny Yeung, UCL Institute of Child Health

Session 4

– Cellular immunotherapy for CMV – chasing the rainbow? – Dr Karl Peggs, UCL Cancer Institute